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GSH provides not only upregulation of VD regulatory genes but also adds to GLUT-4 activation

The result of these cellular injuries manifests clinically as reduced fertilization rates, lower-quality embryos, and increased developmental arrest in PCOS-associated infertility (70)

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Histamine can increase intestinal permeability (leaky gut), leading to bloating, cramping, and digestive distress, such as by causing fluctuating diarrhea and constipation, gas, abdominal pain, and discomfort after eating high-histamine foods

An update on the genetics, clinical presentation, and pathomechanisms of human riboflavin transporter deficiency